There are
501 mi
from St Charles, MO to Ashwaubenon, WI
That's the driving distance. It would take 9 hours 26 mins to go from St Charles, Missouri to Ashwaubenon, Wisconsin.
The flight distance (direct flight from St Charles, MO to Ashwaubenon, WI) is 413.04 mi.
501 mi = 806.57 kms