There are
2,409 mi
from Southfield, MI to San Mateo, CA
That's the driving distance. It would take 1 day 17 hours to go from Southfield, Michigan to San Mateo, California.
The flight distance (direct flight from Southfield, MI to San Mateo, CA) is 2,078.04 mi.
2,409 mi = 3,877.42 kms