There are
1,704 mi
from South San Francisco, CA to South Sioux City, NE
That's the driving distance. It would take 1 day 5 hours to go from South San Francisco, California to South Sioux City, Nebraska.
The flight distance (direct flight from South San Francisco, CA to South Sioux City, NE) is 1,408.30 mi.
1,704 mi = 2,742.98 kms