There are
2,779 mi
from South San Francisco, CA to Hanover, PA
That's the driving distance. It would take 2 days 1 hour to go from South San Francisco, California to Hanover, Pennsylvania.
The flight distance (direct flight from South San Francisco, CA to Hanover, PA) is 2,426.59 mi.
2,779 mi = 4,471.58 kms