There are
486 mi
from Sioux Falls, SD to Waukesha, WI
That's the driving distance. It would take 8 hours 46 mins to go from Sioux Falls, South Dakota to Waukesha, Wisconsin.
The flight distance (direct flight from Sioux Falls, SD to Waukesha, WI) is 427.41 mi.
486 mi = 782.22 kms