There are
937 mi
from Sioux Falls, SD to Twinsburg, OH
That's the driving distance. It would take 17 hours 7 mins to go from Sioux Falls, South Dakota to Twinsburg, Ohio.
The flight distance (direct flight from Sioux Falls, SD to Twinsburg, OH) is 792.23 mi.
937 mi = 1,507.28 kms