There are
1,644 mi
from Sioux Falls, SD to St Petersburg, FL
That's the driving distance. It would take 1 day 6 hours to go from Sioux Falls, South Dakota to St Petersburg, Florida.
The flight distance (direct flight from Sioux Falls, SD to St Petersburg, FL) is 1,341.69 mi.
1,644 mi = 1.61 kms