There are
1,219 mi
from Sioux Falls, SD to Slidell, LA
That's the driving distance. It would take 22 hours 24 mins to go from Sioux Falls, South Dakota to Slidell, Louisiana.
The flight distance (direct flight from Sioux Falls, SD to Slidell, LA) is 992.74 mi.
1,219 mi = 1.61 kms