There are
791 mi
from Sioux Falls, SD to Shelbyville, IN
That's the driving distance. It would take 14 hours 14 mins to go from Sioux Falls, South Dakota to Shelbyville, Indiana.
The flight distance (direct flight from Sioux Falls, SD to Shelbyville, IN) is 629.11 mi.
791 mi = 1,273.65 kms