There are
1,660 mi
from Sioux Falls, SD to San Luis, AZ
That's the driving distance. It would take 1 day 6 hours to go from Sioux Falls, South Dakota to San Luis, Arizona.
The flight distance (direct flight from Sioux Falls, SD to San Luis, AZ) is 1,241.52 mi.
1,660 mi = 1.61 kms