There are
1,741 mi
from Sioux Falls, SD to San Francisco, CA
That's the driving distance. It would take 1 day 5 hours to go from Sioux Falls, South Dakota to San Francisco, California.
The flight distance (direct flight from Sioux Falls, SD to San Francisco, CA) is 1,399.35 mi.
1,741 mi = 1.61 kms