There are
1,524 mi
from Sioux Falls, SD to Reno, NV
That's the driving distance. It would take 1 day 1 hour to go from Sioux Falls, South Dakota to Reno, Nevada.
The flight distance (direct flight from Sioux Falls, SD to Reno, NV) is 1,222.90 mi.
1,524 mi = 1.61 kms