There are
1,203 mi
from Sioux Falls, SD to Radford, VA
That's the driving distance. It would take 22 hours 36 mins to go from Sioux Falls, South Dakota to Radford, Virginia.
The flight distance (direct flight from Sioux Falls, SD to Radford, VA) is 955.67 mi.
1,203 mi = 1.61 kms