There are
1,245 mi
from Sioux Falls, SD to Pottsville, PA
That's the driving distance. It would take 22 hours 48 mins to go from Sioux Falls, South Dakota to Pottsville, Pennsylvania.
The flight distance (direct flight from Sioux Falls, SD to Pottsville, PA) is 1,066.50 mi.
1,245 mi = 1.61 kms