There are
566 mi
from Sioux Falls, SD to Ponca City, OK
That's the driving distance. It would take 10 hours 8 mins to go from Sioux Falls, South Dakota to Ponca City, Oklahoma.
The flight distance (direct flight from Sioux Falls, SD to Ponca City, OK) is 473.24 mi.
566 mi = 910.42 kms