There are
484 mi
from Sioux Falls, SD to Pewaukee, WI
That's the driving distance. It would take 8 hours 43 mins to go from Sioux Falls, South Dakota to Pewaukee, Wisconsin.
The flight distance (direct flight from Sioux Falls, SD to Pewaukee, WI) is 427.75 mi.
484 mi = 779.61 kms