There are
1,844 mi
from Sioux Falls, SD to Palmetto Bay, FL
That's the driving distance. It would take 1 day 9 hours to go from Sioux Falls, South Dakota to Palmetto Bay, Florida.
The flight distance (direct flight from Sioux Falls, SD to Palmetto Bay, FL) is 1,543.66 mi.
1,844 mi = 1.61 kms