There are
1,572 mi
from Sioux Falls, SD to Palm Coast, FL
That's the driving distance. It would take 1 day 4 hours to go from Sioux Falls, South Dakota to Palm Coast, Florida.
The flight distance (direct flight from Sioux Falls, SD to Palm Coast, FL) is 1,287.94 mi.
1,572 mi = 1.61 kms