There are
622 mi
from Sioux Falls, SD to Northglenn, CO
That's the driving distance. It would take 11 hours 31 mins to go from Sioux Falls, South Dakota to Northglenn, Colorado.
The flight distance (direct flight from Sioux Falls, SD to Northglenn, CO) is 495.72 mi.
622 mi = 1,001.75 kms