There are
759 mi
from Sioux Falls, SD to Noblesville, IN
That's the driving distance. It would take 13 hours 57 mins to go from Sioux Falls, South Dakota to Noblesville, Indiana.
The flight distance (direct flight from Sioux Falls, SD to Noblesville, IN) is 601.01 mi.
759 mi = 1,221.99 kms