There are
1,618 mi
from Sioux Falls, SD to New Smyrna Beach, FL
That's the driving distance. It would take 1 day 5 hours to go from Sioux Falls, South Dakota to New Smyrna Beach, Florida.
The flight distance (direct flight from Sioux Falls, SD to New Smyrna Beach, FL) is 1,328.98 mi.
1,618 mi = 1.61 kms