There are
1,299 mi
from Sioux Falls, SD to Mooresville, NC
That's the driving distance. It would take 1 day to go from Sioux Falls, South Dakota to Mooresville, North Carolina.
The flight distance (direct flight from Sioux Falls, SD to Mooresville, NC) is 1,006.87 mi.
1,299 mi = 2,091.29 kms