There are
1,556 mi
from Sioux Falls, SD to Milwaukie, OR
That's the driving distance. It would take 1 day 3 hours to go from Sioux Falls, South Dakota to Milwaukie, Oregon.
The flight distance (direct flight from Sioux Falls, SD to Milwaukie, OR) is 1,279.41 mi.
1,556 mi = 2,503.78 kms