There are
1,457 mi
from Sioux Falls, SD to Middletown, CT
That's the driving distance. It would take 1 day 2 hours to go from Sioux Falls, South Dakota to Middletown, Connecticut.
The flight distance (direct flight from Sioux Falls, SD to Middletown, CT) is 1,227.35 mi.
1,457 mi = 1.61 kms