Miles between Sioux Falls, SD and Mexico, MO

There are
502 mi
from Sioux Falls, SD to Mexico, MO

That's the driving distance. It would take 9 hours 20 mins to go from Sioux Falls, South Dakota to Mexico, Missouri.

The flight distance (direct flight from Sioux Falls, SD to Mexico, MO) is 392.29 mi.

502 mi = 808.37 kms