There are
1,580 mi
from Sioux Falls, SD to Methuen, MA
That's the driving distance. It would take 1 day 5 hours to go from Sioux Falls, South Dakota to Methuen, Massachusetts.
The flight distance (direct flight from Sioux Falls, SD to Methuen, MA) is 1,282.34 mi.
1,580 mi = 1.61 kms