There are
236 mi
from Sioux Falls, SD to Mendota Heights, MN
That's the driving distance. It would take 4 hours 43 mins to go from Sioux Falls, South Dakota to Mendota Heights, Minnesota.
The flight distance (direct flight from Sioux Falls, SD to Mendota Heights, MN) is 198.98 mi.
236 mi = 379.06 kms