There are
930 mi
from Sioux Falls, SD to Mayfield Heights, OH
That's the driving distance. It would take 17 hours 9 mins to go from Sioux Falls, South Dakota to Mayfield Heights, Ohio.
The flight distance (direct flight from Sioux Falls, SD to Mayfield Heights, OH) is 787.44 mi.
930 mi = 1,496.67 kms