There are
976 mi
from Sioux Falls, SD to Lewisburg, TN
That's the driving distance. It would take 17 hours 54 mins to go from Sioux Falls, South Dakota to Lewisburg, Tennessee.
The flight distance (direct flight from Sioux Falls, SD to Lewisburg, TN) is 768.64 mi.
976 mi = 1,571.05 kms