There are
376 mi
from Sioux Falls, SD to Leawood, KS
That's the driving distance. It would take 6 hours 50 mins to go from Sioux Falls, South Dakota to Leawood, Kansas.
The flight distance (direct flight from Sioux Falls, SD to Leawood, KS) is 334.62 mi.
376 mi = 604.66 kms