Miles between Sioux Falls, SD and La Crosse, WI

There are
298 mi
from Sioux Falls, SD to La Crosse, WI

That's the driving distance. It would take 5 hours 26 mins to go from Sioux Falls, South Dakota to La Crosse, Wisconsin.

The flight distance (direct flight from Sioux Falls, SD to La Crosse, WI) is 273.39 mi.

298 mi = 479.37 kms