There are
299 mi
from Sioux Falls, SD to Kearney, NE
That's the driving distance. It would take 5 hours 42 mins to go from Sioux Falls, South Dakota to Kearney, Nebraska.
The flight distance (direct flight from Sioux Falls, SD to Kearney, NE) is 231.68 mi.
299 mi = 480.95 kms