Miles between Sioux Falls, SD and Independence, MO

There are
375 mi
from Sioux Falls, SD to Independence, MO

That's the driving distance. It would take 6 hours 46 mins to go from Sioux Falls, South Dakota to Independence, Missouri.

The flight distance (direct flight from Sioux Falls, SD to Independence, MO) is 330.07 mi.

375 mi = 603.52 kms