There are
1,227 mi
from Sioux Falls, SD to Hendersonville, NC
That's the driving distance. It would take 22 hours 43 mins to go from Sioux Falls, South Dakota to Hendersonville, North Carolina.
The flight distance (direct flight from Sioux Falls, SD to Hendersonville, NC) is 946.91 mi.
1,227 mi = 1,974.71 kms