There are
1,262 mi
from Sioux Falls, SD to Harrisonburg, VA
That's the driving distance. It would take 23 hours 27 mins to go from Sioux Falls, South Dakota to Harrisonburg, Virginia.
The flight distance (direct flight from Sioux Falls, SD to Harrisonburg, VA) is 991.91 mi.
1,262 mi = 1.61 kms