There are
1,460 mi
from Sioux Falls, SD to Hanahan, SC
That's the driving distance. It would take 1 day 3 hours to go from Sioux Falls, South Dakota to Hanahan, South Carolina.
The flight distance (direct flight from Sioux Falls, SD to Hanahan, SC) is 1,161.84 mi.
1,460 mi = 1.61 kms