There are
1,060 mi
from Sioux Falls, SD to Greensburg, PA
That's the driving distance. It would take 19 hours 27 mins to go from Sioux Falls, South Dakota to Greensburg, Pennsylvania.
The flight distance (direct flight from Sioux Falls, SD to Greensburg, PA) is 908.48 mi.
1,060 mi = 1.61 kms