There are
1,297 mi
from Sioux Falls, SD to Greensboro, NC
That's the driving distance. It would take 1 day to go from Sioux Falls, South Dakota to Greensboro, North Carolina.
The flight distance (direct flight from Sioux Falls, SD to Greensboro, NC) is 1,032.62 mi.
1,297 mi = 2,087.64 kms