There are
618 mi
from Sioux Falls, SD to Godfrey, IL
That's the driving distance. It would take 11 hours 25 mins to go from Sioux Falls, South Dakota to Godfrey, Illinois.
The flight distance (direct flight from Sioux Falls, SD to Godfrey, IL) is 463.67 mi.
618 mi = 995.26 kms