There are
553 mi
from Sioux Falls, SD to Glendale Heights, IL
That's the driving distance. It would take 10 hours 2 mins to go from Sioux Falls, South Dakota to Glendale Heights, Illinois.
The flight distance (direct flight from Sioux Falls, SD to Glendale Heights, IL) is 451.56 mi.
553 mi = 889.24 kms