There are
601 mi
from Sioux Falls, SD to Fayetteville, AR
That's the driving distance. It would take 10 hours 55 mins to go from Sioux Falls, South Dakota to Fayetteville, Arkansas.
The flight distance (direct flight from Sioux Falls, SD to Fayetteville, AR) is 534.57 mi.
601 mi = 967.76 kms