There are
604 mi
from Sioux Falls, SD to Escanaba, MI
That's the driving distance. It would take 11 hours 43 mins to go from Sioux Falls, South Dakota to Escanaba, Michigan.
The flight distance (direct flight from Sioux Falls, SD to Escanaba, MI) is 496.97 mi.
604 mi = 971.64 kms