There are
330 mi
from Sioux Falls, SD to Chippewa Falls, WI
That's the driving distance. It would take 6 hours 25 mins to go from Sioux Falls, South Dakota to Chippewa Falls, Wisconsin.
The flight distance (direct flight from Sioux Falls, SD to Chippewa Falls, WI) is 279.57 mi.
330 mi = 531.24 kms