There are
813 mi
from Sioux Falls, SD to Ann Arbor, MI
That's the driving distance. It would take 14 hours 56 mins to go from Sioux Falls, South Dakota to Ann Arbor, Michigan.
The flight distance (direct flight from Sioux Falls, SD to Ann Arbor, MI) is 660.80 mi.
813 mi = 1,307.69 kms