There are
489 mi
from Sioux City, IA to Wentzville, MO
That's the driving distance. It would take 9 hours 2 mins to go from Sioux City, Iowa to Wentzville, Missouri.
The flight distance (direct flight from Sioux City, IA to Wentzville, MO) is 386.50 mi.
489 mi = 786.40 kms