There are
522 mi
from Sioux City, IA to Webster Groves, MO
That's the driving distance. It would take 9 hours 45 mins to go from Sioux City, Iowa to Webster Groves, Missouri.
The flight distance (direct flight from Sioux City, IA to Webster Groves, MO) is 416.40 mi.
522 mi = 840.80 kms