There are
740 mi
from Sioux City, IA to Southaven, MS
That's the driving distance. It would take 14 hours 24 mins to go from Sioux City, Iowa to Southaven, Mississippi.
The flight distance (direct flight from Sioux City, IA to Southaven, MS) is 622.31 mi.
740 mi = 1,191.02 kms