There are
735 mi
from Sioux City, IA to Seymour, IN
That's the driving distance. It would take 13 hours 25 mins to go from Sioux City, Iowa to Seymour, Indiana.
The flight distance (direct flight from Sioux City, IA to Seymour, IN) is 601.66 mi.
735 mi = 1,183.12 kms