There are
367 mi
from Sioux City, IA to Sedalia, MO
That's the driving distance. It would take 6 hours 53 mins to go from Sioux City, Iowa to Sedalia, Missouri.
The flight distance (direct flight from Sioux City, IA to Sedalia, MO) is 310.52 mi.
367 mi = 591.26 kms