There are
1,145 mi
from Sioux City, IA to Roanoke, VA
That's the driving distance. It would take 21 hours 51 mins to go from Sioux City, Iowa to Roanoke, Virginia.
The flight distance (direct flight from Sioux City, IA to Roanoke, VA) is 942.43 mi.
1,145 mi = 1.61 kms